Drugs
Potassium chloride 7,46% - 10% - 15% - 20% Injectable Ampoule

Presentation
Volume | Concentration |
10ml | 7,46 % |
10 ml | 10 % |
20 ml | 10 % |
10 ml | 15 % |
10 ml | 20 % |
20 ml | 20 % |
Pharmacodynamics
Potassium supplement
In terms of laboratory tests, an hypokalaemia lower than 3.6 mmol/l indicates potassium deficiency.
This deficiency can affect:
- the digestive tract : diarrhoea, vomiting, stimulating laxatives.
- the renal system: increased excretion in the urine in case of congenital tubular disease or during therapy by salidiuretics, corticoids or (IV) amphotericin B, by excessive alkaline or liquorice derivatives consumption.
- the endocrine system : primary hyperaldosteronism (that involves etiologic treatment).
Symptomatic potassium deficiency may produce some of the followings symptoms: muscular fatigability, pseudoparalysis, cramping and ECG modification, repolarisation disorders and ventricular hyperexcitability.
Chloride ion : correction of metabolic alkalosis often associated with hypokalaemia.
Therapeutic Indications of potassium chloride
- Potassium supplement to meet the patient's daily needs in parenteral nutrition.
- Treatment of hypokalaemia and adjustment of potassium depletion, in case of severe disorders or when intake by enteral route cannot be achieved or is inadequate.
NB: IV administration of potassium salt leads to a high potassium gradient which can cause hyperkalaemia and heart failure (see Posology and administration).
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